| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-5 [D153N] |
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| Ligand | BDBM50154252 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1560413 (CHEMBL3776074) |
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| IC50 | 122±n/a nM |
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| Citation |  Hoelz, LV; Zorzanelli, BC; Azevedo, PH; Passos, SG; de Souza, LR; Zani, M; Pinheiro, S; Puzer, L; Dias, LR; Muri, EM Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5. Eur J Med Chem112:39-47 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-5 [D153N] |
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| Name: | Kallikrein-5 [D153N] |
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| Synonyms: | KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32031.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282456 |
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| Residue: | 293 |
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| Sequence: | MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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| BDBM50154252 |
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| n/a |
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| Name | BDBM50154252 |
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| Synonyms: | CHEMBL3774934 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H32N2O6 |
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| Mol. Mass. | 420.4993 |
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| SMILES | COC(=O)[C@@H]1CCCN1C(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C |r| |
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| Structure | 
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