| Reaction Details |
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 | Report a problem with these data |
| Target | Dual-specificity tyrosine-phosphorylation regulated kinase 2 |
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| Ligand | BDBM50154348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1560174 |
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| IC50 | 60±n/a nM |
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| Citation |  Mariano M; Hartmann RW; Engel M Systematic diversification of benzylidene heterocycles yields novel inhibitor scaffolds selective for Dyrk1A, Clk1 and CK2. Eur J Med Chem 112:209-16 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual-specificity tyrosine-phosphorylation regulated kinase 2 |
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| Name: | Dual-specificity tyrosine-phosphorylation regulated kinase 2 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66690.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508025 |
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| Residue: | 601 |
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| Sequence: | MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNA
AAAAHTIGGSKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLP
VVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPE
IYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAY
DHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMT
FELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQG
RSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYP
LLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGG
RSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLP
KPPTGEKTSVKRITESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLV
S
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| BDBM50154348 |
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| n/a |
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| Name | BDBM50154348 |
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| Synonyms: | CHEMBL3774704 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9NO2S |
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| Mol. Mass. | 231.27 |
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| SMILES | O=C1OCC\C1=C/c1ccc2ncsc2c1 |
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| Structure | 
|
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