| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hepatocyte growth factor activator |
|---|
| Ligand | BDBM50158153 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1565754 (CHEMBL3782552) |
|---|
| Ki | 380±n/a nM |
|---|
| Citation |  Venukadasula, PK; Owusu, BY; Bansal, N; Ross, LJ; Hobrath, JV; Bao, D; Truss, JW; Stackhouse, M; Messick, TE; Klampfer, L; Galemmo, RA Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation. ACS Med Chem Lett7:177-81 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Hepatocyte growth factor activator |
|---|
| Name: | Hepatocyte growth factor activator |
|---|
| Synonyms: | HGF activator | HGFA | HGFAC | HGFA_HUMAN | Hepatocyte growth factor activator | Hepatocyte growth factor activator long chain | Hepatocyte growth factor activator short chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 70690.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109514 |
|---|
| Residue: | 655 |
|---|
| Sequence: | MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV
TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH
ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD
PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT
RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST
SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE
YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP
WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE
KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW
GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG
PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
|
|
|
|---|
| BDBM50158153 |
|---|
| n/a |
|---|
| Name | BDBM50158153 |
|---|
| Synonyms: | CHEMBL3780548 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H38N6O2 |
|---|
| Mol. Mass. | 538.6831 |
|---|
| SMILES | NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NC(=O)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
