Reaction Details |
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Target | Proteasome subunit beta type-5 |
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Ligand | BDBM50160869 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1567337 (CHEMBL3789477) |
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IC50 | 1.0±n/a nM |
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Citation | Shi, J; Lei, M; Wu, W; Feng, H; Wang, J; Chen, S; Zhu, Y; Hu, S; Liu, Z; Jiang, C Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed fromaa- andaß-amino acids. Bioorg Med Chem Lett26:1958-62 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Proteasome subunit beta type-5 |
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Name: | Proteasome subunit beta type-5 |
Synonyms: | 20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X |
Type: | Protein |
Mol. Mass.: | 28480.96 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 263 |
Sequence: | MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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BDBM50160869 |
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n/a |
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Name | BDBM50160869 |
Synonyms: | CHEMBL3786398 |
Type | Small organic molecule |
Emp. Form. | C25H32BFN2O4 |
Mol. Mass. | 454.342 |
SMILES | CC(C)C[C@@H](NC(=O)CC(NC(=O)[C@H]1CCCc2ccccc12)c1cccc(F)c1)B(O)O |r| |
Structure |
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