| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM50161482 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1567404 (CHEMBL3790087) |
|---|
| Ki | 1.7±n/a nM |
|---|
| Citation |  Özgeris, B; Göksu, S; Polat Köse, L; Gülçin, I; Salmas, RE; Durdagi, S; Tümer, F; Supuran, CT Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds. Bioorg Med Chem24:2318-29 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67792.70 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22303 |
|---|
| Residue: | 614 |
|---|
| Sequence: | MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
|
|
|
|---|
| BDBM50161482 |
|---|
| n/a |
|---|
| Name | BDBM50161482 |
|---|
| Synonyms: | CHEMBL3785207 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H18N2O2 |
|---|
| Mol. Mass. | 234.2942 |
|---|
| SMILES | CN(C)C(=O)N[C@H]1CCc2ccc(O)cc2C1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
