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TargetCarbonic anhydrase 7
LigandBDBM50163864
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1572868
KON 440000 M-1s-1
Citation Talibov VOLinkuviene VMatulis DDanielson UH Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. J Med Chem 59:2083-93 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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  Blast E-value cutoff:
BDBM50163864
n/a
NameBDBM50163864
Synonyms:3-(1H-benzimidazol-1-ylacetyl)benzenesulfonamide (3a) | CHEMBL3799296 | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 3
TypeSmall organic molecule
Emp. Form.C15H13N3O3S
Mol. Mass.315.347
SMILESNS(=O)(=O)c1cccc(c1)C(=O)Cn1cnc2ccccc12
Structure
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