Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCarbonic anhydrase 7
LigandBDBM50163859
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1572868
KON 20000 M-1s-1
Citation Talibov VOLinkuviene VMatulis DDanielson UH Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. J Med Chem 59:2083-93 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50163859
n/a
NameBDBM50163859
Synonyms:CHEMBL3797835 | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 12
TypeSmall organic molecule
Emp. Form.C17H25F3N2O2S2
Mol. Mass.410.518
SMILESCCCSc1c(F)c(F)c(c(NC2CCCCCCC2)c1F)S(N)(=O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: