| Reaction Details |
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 | Report a problem with these data |
| Target | Calmodulin |
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| Ligand | BDBM50017698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1576535 (CHEMBL3803975) |
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| Kd | 3500±n/a nM |
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| Citation |  Bruno, C; Cavalluzzi, MM; Rusciano, MR; Lovece, A; Carrieri, A; Pracella, R; Giannuzzi, G; Polimeno, L; Viale, M; Illario, M; Franchini, C; Lentini, G The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II. Eur J Med Chem116:36-45 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calmodulin |
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| Name: | Calmodulin |
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| Synonyms: | CALM | CALM_BOVIN | CAM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 16813.73 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1458985 |
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| Residue: | 149 |
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| Sequence: | MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK
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| BDBM50017698 |
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| n/a |
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| Name | BDBM50017698 |
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| Synonyms: | 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide | 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide | 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide(loperamide) | CHEMBL841 | Imodium | LOPERAMIDE | LOPERAMIDE HYDROCHLORIDE | cid_71420 | med.21724, Compound 184 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33ClN2O2 |
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| Mol. Mass. | 477.038 |
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| SMILES | CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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