| Reaction Details |
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 | Report a problem with these data |
| Target | Calmodulin |
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| Ligand | BDBM50017696 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1576539 (CHEMBL3803979) |
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| IC50 | 60000±n/a nM |
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| Citation |  Bruno, C; Cavalluzzi, MM; Rusciano, MR; Lovece, A; Carrieri, A; Pracella, R; Giannuzzi, G; Polimeno, L; Viale, M; Illario, M; Franchini, C; Lentini, G The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II. Eur J Med Chem116:36-45 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calmodulin |
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| Name: | Calmodulin |
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| Synonyms: | CALM | CALM_BOVIN | CAM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 16813.73 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1458985 |
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| Residue: | 149 |
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| Sequence: | MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
EVDEMIREADIDGDGQVNYEEFVQMMTAK
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|
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| BDBM50017696 |
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| n/a |
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| Name | BDBM50017696 |
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| Synonyms: | (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine | 10-(2-Dimethylaminopropyl)phenothiazine | 10-[2-(dimethylamino)propyl]phenothiazine | CHEMBL643 | N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine | N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine | PROMETHAZINE | med.21724, Compound 16 | proazamine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N2S |
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| Mol. Mass. | 284.419 |
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| SMILES | CC(CN1c2ccccc2Sc2ccccc12)N(C)C |
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| Structure | 
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