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TargetSphingosine 1-phosphate receptor 3
LigandBDBM50165371
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1573232
EC50 1700±n/a nM
Citation Lescop CMüller CMathys BBirker Mde Kanter RKohl CHess PNayler ORey MSieber PSteiner BWeller TBolli MH Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups. Eur J Med Chem 116:222-238 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 3
Name:Sphingosine 1-phosphate receptor Edg-5/Sphingosine 1-phosphate receptor Edg-3
Synonyms:EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42278.13
Organism:Homo sapiens (Human)
Description:Q99500
Residue:378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
SSCIMDKNAALQNGIFCN
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  Blast E-value cutoff:
BDBM50165371
n/a
NameBDBM50165371
Synonyms:CHEMBL3797357
TypeSmall organic molecule
Emp. Form.C25H34N4O6S
Mol. Mass.518.626
SMILESCCc1cc(cc(C)c1OC[C@@H](O)CNC(=O)CO)-c1noc(n1)-c1cc(C)c(CN(C)CCO)s1 |r|
Structure
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