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TargetDeath-associated protein kinase 3
LigandBDBM50166260
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1575380 (CHEMBL3802098)
IC50>10000±n/a nM
Citation Jung, MEByun, BJKim, HMLee, JYPark, JHLee, NSon, YHChoi, SUYang, KMKim, SJLee, KKim, YCChoi, G Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening. Bioorg Med Chem Lett26:2719-23 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Death-associated protein kinase 3
Name:Death-associated protein kinase 3
Synonyms:DAP kinase 3 | DAP-like kinase | DAPK3 | DAPK3_HUMAN | ZIP-kinase | ZIPK
Type:PROTEIN
Mol. Mass.:52537.07
Organism:Homo sapiens (Human)
Description:ChEMBL_586564
Residue:454
Sequence:
MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE
IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL
KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY
FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTT
RLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIY
EEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRY
EALAKQVASEMRFVQDLVRALEQEKLQGVECGLR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50166260
n/a
NameBDBM50166260
Synonyms:CHEMBL3799505
TypeSmall organic molecule
Emp. Form.C22H22N4O3
Mol. Mass.390.4351
SMILESCC(C)(C)CC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1
Structure
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