| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50166976 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1573519 (CHEMBL3801474) |
|---|
| Ki | 6.3±n/a nM |
|---|
| Citation |  Weichert, D; Stanek, M; Hübner, H; Gmeiner, P Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem24:2641-53 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50166976 |
|---|
| n/a |
|---|
| Name | BDBM50166976 |
|---|
| Synonyms: | CHEMBL3799455 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H32N2O4 |
|---|
| Mol. Mass. | 472.5754 |
|---|
| SMILES | COc1cc(CCNCCc2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
