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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Microtubule-associated protein 2 | ||
| Ligand | BDBM50167279 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1573781 (CHEMBL3803202) | ||
| EC50 | 20±n/a nM | ||
| Citation |  McBride, C; Cheruvallath, Z; Komandla, M; Tang, M; Farrell, P; Lawson, JD; Vanderpool, D; Wu, Y; Dougan, DR; Plonowski, A; Holub, C; Larson, C Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2. Bioorg Med Chem Lett26:2779-2783 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Microtubule-associated protein 2 | |||
| Name: | Microtubule-associated protein 2 | ||
| Synonyms: | MAP-2 | MAP2 | MTAP2_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 199423.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_107603 | ||
| Residue: | 1827 | ||
| Sequence: |
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| BDBM50167279 | |||
| n/a | |||
| Name | BDBM50167279 | ||
| Synonyms: | CHEMBL3799090 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H17FN4O2 | ||
| Mol. Mass. | 352.3623 | ||
| SMILES | Cc1cc(ccc1-n1c2cn[nH]c2c2cc(F)ccc12)C(=O)NCCO |(-2.81,-3.89,;-1.69,-4.4,;-1.54,-5.93,;-.14,-6.58,;1.11,-5.68,;.97,-4.15,;-.44,-3.51,;-.45,-1.97,;.76,-1.05,;2.33,-1.05,;2.8,.38,;1.54,1.31,;.31,.38,;-1.24,.38,;-2.28,1.57,;-3.78,1.21,;-4.58,2.15,;-4.28,,;-3.23,-1.4,;-1.71,-1.05,;0,-8.11,;1.12,-8.62,;-1.26,-9,;-1.11,-10.54,;-2.37,-11.43,;-2.26,-12.65,)| | ||
| Structure | 
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