Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM53132 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1574566 (CHEMBL3804638) |
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Ki | 26600±n/a nM |
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Citation | Cisneros, JA; Robertson, MJ; Valhondo, M; Jorgensen, WL Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett26:2764-2767 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM53132 |
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n/a |
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Name | BDBM53132 |
Synonyms: | 4-(2-imidazo[1,2-a]pyridinyl)benzene-1,2-diol | 4-Imidazo[1,2-a]pyridin-2-yl-benzene-1,2-diol | 4-imidazo[1,2-a]pyridin-2-ylbenzene-1,2-diol | 4-imidazo[1,2-a]pyridin-2-ylpyrocatechol | MLS001208128 | SMR000516824 | cid_764266 |
Type | Small organic molecule |
Emp. Form. | C13H10N2O2 |
Mol. Mass. | 226.2307 |
SMILES | Oc1ccc(cc1O)-c1cn2ccccc2n1 |
Structure |
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