| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic triacylglycerol lipase |
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| Ligand | BDBM24567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1575199 (CHEMBL3800919) |
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| IC50 | 12±n/a nM |
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| Citation |  Ha, MT; Tran, MH; Ah, KJ; Jo, KJ; Kim, J; Kim, WD; Cheon, WJ; Woo, MH; Ryu, SH; Min, BS Potential pancreatic lipase inhibitory activity of phenolic constituents from the root bark of Morus alba L. Bioorg Med Chem Lett26:2788-2794 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic triacylglycerol lipase |
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| Name: | Pancreatic triacylglycerol lipase |
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| Synonyms: | LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase |
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| Type: | Enzyme |
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| Mol. Mass.: | 50080.69 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00591 |
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| Residue: | 450 |
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| Sequence: | SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTI
TNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQ
NIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAE
PCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQK
NILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC
PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSL
FGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASK
ITVERNDGKVYDFCSQETVREEVLLTLNPC
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| BDBM24567 |
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| n/a |
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| Name | BDBM24567 |
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| Synonyms: | (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate | CHEMBL175247 | Orlistat | THLP | Tetrahydrolipstatin | US9328123, Orlistat | Xenical |
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| Type | Small organic molecule |
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| Emp. Form. | C29H53NO5 |
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| Mol. Mass. | 495.7348 |
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| SMILES | CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O |r| |
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| Structure | 
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