| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
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| Ligand | BDBM23163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1578114 (CHEMBL3807069) |
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| EC50 | 0.090000±n/a nM |
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| Citation |  Dhar, TG; Xiao, HY; Xie, J; Lehman-McKeeman, LD; Wu, DR; Dabros, M; Yang, X; Taylor, TL; Zhou, XD; Heimrich, EM; Thomas, R; McIntyre, KW; Warrack, B; Shi, H; Levesque, PC; Zhu, JL; Hennan, J; Balimane, P; Yang, Z; Marino, AM; Cornelius, G; D'Arienzo, CJ; Mathur, A; Shen, DR; Cvijic, ME; Salter-Cid, L; Barrish, JC; Carter, PH; Dyckman, AJ Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials. ACS Med Chem Lett7:283-8 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 4 |
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| Name: | Sphingosine 1-phosphate receptor 4 |
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| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41647.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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| BDBM23163 |
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| n/a |
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| Name | BDBM23163 |
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| Synonyms: | CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propoxy}phosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C19H34NO5P |
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| Mol. Mass. | 387.4507 |
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| SMILES | CCCCCCCCc1ccc(CCC(N)(CO)COP(O)(O)=O)cc1 |
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| Structure | 
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