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TargetD-amino-acid oxidase
LigandBDBM31148
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1577592
IC50 43±n/a nM
Citation Xie DLu JXie JCui JLi TFWang YCChen YGong NLi XYFu LWang YX Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor. Eur J Med Chem 117:19-32 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
D-amino-acid oxidase
Name:D-amino-acid oxidase
Synonyms:D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO
Type:Homodimer
Mol. Mass.:39476.06
Organism:Homo sapiens (Human)
Description:n/a
Residue:347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM31148
n/a
NameBDBM31148
Synonyms:3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1
TypeSmall organic molecule
Emp. Form.C9H7NO2
Mol. Mass.161.1574
SMILESOc1cc2ccccc2[nH]c1=O
Structure
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