| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM50170228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1577590 (CHEMBL3807134) |
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| IC50 | 220±n/a nM |
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| Citation |  Xie, D; Lu, J; Xie, J; Cui, J; Li, TF; Wang, YC; Chen, Y; Gong, N; Li, XY; Fu, L; Wang, YX Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor. Eur J Med Chem117:19-32 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG |
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| Type: | Flavoprotein |
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| Mol. Mass.: | 39338.01 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Homodimer. |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPS
NPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPR
ELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIIN
CTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGG
TFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
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| BDBM50170228 |
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| n/a |
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| Name | BDBM50170228 |
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| Synonyms: | CHEMBL3804953 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H4BrN3O2 |
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| Mol. Mass. | 242.03 |
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| SMILES | Brc1ccnc2[nH]c(=O)c(=O)[nH]c12 |
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| Structure | 
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