| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50170914 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1578163 (CHEMBL3807245) |
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| IC50 | 1820±n/a nM |
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| Citation |  Billamboz, M; Suchaud, V; Bailly, F; Lion, C; Andréola, ML; Christ, F; Debyser, Z; Cotelle, P 2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4. Eur J Med Chem117:256-68 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50170914 |
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| n/a |
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| Name | BDBM50170914 |
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| Synonyms: | CHEMBL3805355 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14N2O4 |
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| Mol. Mass. | 262.2613 |
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| SMILES | CCCNC(=O)C1C(=O)N(O)C(=O)c2ccccc12 |
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| Structure | 
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