| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
|---|
| Ligand | BDBM50174175 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1578757 (CHEMBL3812678) |
|---|
| Ki | 630±n/a nM |
|---|
| Citation |  Zhai, L; Zhang, YL; Kang, JS; Oelschlaeger, P; Xiao, L; Nie, SS; Yang, KW Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-ß-Lactmase-1 (NDM-1) Inhibitors. ACS Med Chem Lett7:413-7 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase type 2 |
|---|
| Name: | Metallo-beta-lactamase type 2 |
|---|
| Synonyms: | B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28498.15 |
|---|
| Organism: | Klebsiella pneumoniae |
|---|
| Description: | ChEMBL_103887 |
|---|
| Residue: | 270 |
|---|
| Sequence: | MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ
HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH
AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL
KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF
PKASMIVMSHSAPDSRAAITHTARMADKLR
|
|
|
|---|
| BDBM50174175 |
|---|
| n/a |
|---|
| Name | BDBM50174175 |
|---|
| Synonyms: | CHEMBL3808813 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H13ClN4O2S |
|---|
| Mol. Mass. | 360.818 |
|---|
| SMILES | Oc1ccc(cc1)-c1nnc(SCC(=O)Nc2cccc(Cl)c2)[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
