| Reaction Details |
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 | Report a problem with these data |
| Target | Large neutral amino acids transporter small subunit 1 |
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| Ligand | BDBM50174345 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1579725 (CHEMBL3811918) |
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| IC50 | 7300±n/a nM |
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| Citation |  Augustyn, E; Finke, K; Zur, AA; Hansen, L; Heeren, N; Chien, HC; Lin, L; Giacomini, KM; Colas, C; Schlessinger, A; Thomas, AA LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. Bioorg Med Chem Lett26:2616-2621 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Large neutral amino acids transporter small subunit 1 |
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| Name: | Large neutral amino acids transporter small subunit 1 |
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| Synonyms: | 4F2 LC | 4F2 light chain | 4F2LC | CD98 light chain | CD98LC | CD98LC | Integral membrane protein E16 | L-type amino acid transporter 1 | LAT1 | LAT1_HUMAN | Large neutral amino acids transporter small subunit 1 | MPE16 | SLC7A5 | Solute carrier family 7 member 5 | hLAT1 | y+ system cationic amino acid transporter |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55013.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_100160 |
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| Residue: | 507 |
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| Sequence: | MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
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| BDBM50174345 |
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| n/a |
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| Name | BDBM50174345 |
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| Synonyms: | CHEMBL3809112 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17NO2 |
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| Mol. Mass. | 255.3117 |
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| SMILES | N[C@@H](Cc1cccc(Cc2ccccc2)c1)C(O)=O |r| |
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| Structure | 
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