| Reaction Details |
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 | Report a problem with these data |
| Target | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Ligand | BDBM260159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1581728 (CHEMBL3816159) |
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| IC50 | 830±n/a nM |
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| Citation |  Xin, BT; Schimmack, G; Du, Y; Florea, BI; van der Marel, GA; Driessen, C; Krappmann, D; Overkleeft, HS Development of new Malt1 inhibitors and probes. Bioorg Med Chem24:3312-29 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Name: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
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| Synonyms: | MALT lymphoma-associated translocation | MALT lymphoma-associated translocation (MALT1) | MALT1 | MALT1_HUMAN | MLT | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Paracaspase |
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| Type: | Enzyme |
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| Mol. Mass.: | 92257.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UDY8 |
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| Residue: | 824 |
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| Sequence: | MSLLGDPLQALPPSAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAEL
AGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQ
LLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAV
HVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMP
GSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQD
SKKVEIIIGRTDEAVECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLK
APLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENF
GNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDAL
KVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCH
LTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQI
QLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVS
KDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRG
LGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCS
RTPDAFISSFAHHASCHFSRSNVPVETTDEIPFSFSDRLRISEK
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| BDBM260159 |
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| n/a |
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| Name | BDBM260159 |
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| Synonyms: | BDBM50177661 | US9504692, Mepezine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2S |
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| Mol. Mass. | 310.456 |
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| SMILES | CN1CCCC(CN2c3ccccc3Sc3ccccc23)C1 |
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| Structure | 
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