| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
|---|
| Ligand | BDBM50178616 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1583489 (CHEMBL3815560) |
|---|
| IC50 | 150±n/a nM |
|---|
| Citation |  Esvan, YJ; Giraud, F; Pereira, E; Suchaud, V; Nauton, L; Théry, V; Dezhenkova, LG; Kaluzhny, DN; Mazov, VN; Shtil, AA; Anizon, F; Moreau, P Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c. Bioorg Med Chem24:3116-24 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-1 |
|---|
| Name: | Serine/threonine-protein kinase pim-1 |
|---|
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35681.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11309 |
|---|
| Residue: | 313 |
|---|
| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
|
|
|
|---|
| BDBM50178616 |
|---|
| n/a |
|---|
| Name | BDBM50178616 |
|---|
| Synonyms: | CHEMBL3814423 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H12N4 |
|---|
| Mol. Mass. | 296.3254 |
|---|
| SMILES | c1n[nH]c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21 |
|---|
| Structure | 
|
|---|
Search and Browse
