| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium channel subfamily K member 2 |
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| Ligand | BDBM79172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1584411 (CHEMBL3819954) |
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| IC50 | 2000±n/a nM |
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| Citation |  Vivier, D; Bennis, K; Lesage, F; Ducki, S Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? J Med Chem59:5149-57 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium channel subfamily K member 2 |
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| Name: | Potassium channel subfamily K member 2 |
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| Synonyms: | KCNK2 | KCNK2_HUMAN | Outward rectifying potassium channel protein TREK-1 | TREK | TREK-1 K(+) channel subunit | TREK1 | Twik-RElated Potassium (K+) channel 1 (TREK1) | Two pore domain potassium channel TREK-1 | Two pore potassium channel TPKC1 |
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| Type: | Protein |
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| Mol. Mass.: | 47099.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95069 |
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| Residue: | 426 |
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| Sequence: | MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWK
TVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQ
IVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALL
GIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVAL
PAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYF
AAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATS
IKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIA
VIENIK
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| BDBM79172 |
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| n/a |
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| Name | BDBM79172 |
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| Synonyms: | 2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol;hydrochloride | 2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol;hydrochloride | 2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazino]ethanol;hydrochloride | Fluphenthixol | MLS001332581 | SMR000875208 | cid_10140115 | cis-(Z)-Flupenthixol dihydrochloride |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25F3N2OS |
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| Mol. Mass. | 434.518 |
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| SMILES | OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
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| Structure | 
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