| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium two pore domain channel subfamily K member 2 |
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| Ligand | BDBM50180663 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1584412 (CHEMBL3819955) |
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| IC50 | 750±n/a nM |
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| Citation |  Vivier, D; Bennis, K; Lesage, F; Ducki, S Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? J Med Chem59:5149-57 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium two pore domain channel subfamily K member 2 |
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| Name: | Potassium two pore domain channel subfamily K member 2 |
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| Synonyms: | Potassium channel subfamily K member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45443.30 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_620769 |
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| Residue: | 411 |
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| Sequence: | MAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLII
GATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNT
SNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQ
LGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALD
AIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIS
KKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQ
ELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK
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| BDBM50180663 |
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| n/a |
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| Name | BDBM50180663 |
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| Synonyms: | CHEBI:7572 | CHEMBL1275655 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H39N3O6 |
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| Mol. Mass. | 609.7114 |
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| SMILES | COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1 |c:4,9| |
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| Structure | 
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