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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50181297
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1584466 (CHEMBL3820113)
Ki 1.6±n/a nM
Citation Weber, FBrune, SBörgel, FLange, CKorpis, KBednarski, PJLaurini, EFermeglia, MPricl, SSchepmann, DWünsch, B Rigidity versus Flexibility: Is This an Issue ins1 Receptor Ligand Affinity and Activity? J Med Chem59:5505-19 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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BDBM50181297
n/a
NameBDBM50181297
Synonyms:CHEMBL3819489
TypeSmall organic molecule
Emp. Form.C20H30N2O
Mol. Mass.314.465
SMILES[H][C@]12C[C@H](O)[C@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8|
Structure
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