Reaction Details |
| Report a problem with these data |
Target | Sigma non-opioid intracellular receptor 1 |
---|
Ligand | BDBM50181297 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1584466 (CHEMBL3820113) |
---|
Ki | 1.6±n/a nM |
---|
Citation | Weber, F; Brune, S; Börgel, F; Lange, C; Korpis, K; Bednarski, PJ; Laurini, E; Fermeglia, M; Pricl, S; Schepmann, D; Wünsch, B Rigidity versus Flexibility: Is This an Issue ins1 Receptor Ligand Affinity and Activity? J Med Chem59:5505-19 (2016) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Sigma non-opioid intracellular receptor 1 |
---|
Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
BDBM50181297 |
---|
n/a |
---|
Name | BDBM50181297 |
Synonyms: | CHEMBL3819489 |
Type | Small organic molecule |
Emp. Form. | C20H30N2O |
Mol. Mass. | 314.465 |
SMILES | [H][C@]12C[C@H](O)[C@]([H])(CN1Cc1ccccc1)N(CC1CCCCC1)C2 |r,THB:4:3:16.24:7.8| |
Structure |
|