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TargetNeuraminidase
LigandBDBM50182249
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1585711
IC50 3.1±n/a nM
Citation Sriwilaijaroen NMagesh SImamura AAndo HIshida HSakai MIshitsubo EHori TMoriya SIshikawa TKuwata KOdagiri TTashiro MHiramatsu HTsukamoto KMiyagi TTokiwa HKiso MSuzuki Y A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions. J Med Chem 59:4563-77 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Neuraminidase
Name:Neuraminidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:49673.59
Organism:Influenza A virus
Description:ChEMBL_1347422
Residue:453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGSITYKVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSRGTFKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDDGAVAVLKYNGIITETIKSWRKNILRTQESECTCVNGSCFTIMTDGPSDGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYKIGY
ICSGVFGDNPRPKDGTGSCGPVSADGANGVKGFSYKYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSMRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGLPEENAI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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  Blast E-value cutoff:
BDBM50182249
n/a
NameBDBM50182249
Synonyms:CHEMBL3818159
TypeSmall organic molecule
Emp. Form.C15H29N2O8P
Mol. Mass.396.3731
SMILESOP(O)(O)=O.CCC(CC)OC[C@@H]1CC(=C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:13|
Structure
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