| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50183070 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1586232 (CHEMBL3820050) |
|---|
| Ki | 1.6±n/a nM |
|---|
| Citation |  Etukala, JR; Zhu, XY; Eyunni, SV; Onyameh, EK; Ofori, E; Bricker, BA; Kang, HJ; Huang, XP; Roth, BL; Ablordeppey, SY Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores. Bioorg Med Chem24:3671-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50183070 |
|---|
| n/a |
|---|
| Name | BDBM50183070 |
|---|
| Synonyms: | CHEMBL3818478 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H30N4O |
|---|
| Mol. Mass. | 402.5319 |
|---|
| SMILES | O=C1NCN(c2ccccc2)C11CCN(CCCCc2c[nH]c3ccccc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
