| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50183266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586241 (CHEMBL3820059) |
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| Ki | 0.027000±n/a nM |
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| Citation |  Etukala, JR; Zhu, XY; Eyunni, SV; Onyameh, EK; Ofori, E; Bricker, BA; Kang, HJ; Huang, XP; Roth, BL; Ablordeppey, SY Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores. Bioorg Med Chem24:3671-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50183266 |
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| n/a |
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| Name | BDBM50183266 |
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| Synonyms: | Anquil | Benperidol | Benquil | MCN-JR-4584 | R-4584 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24FN3O2 |
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| Mol. Mass. | 381.4433 |
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| SMILES | Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 |
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| Structure | 
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