| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 2 |
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| Ligand | BDBM50183448 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586794 |
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| IC50 | >100000±n/a nM |
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| Citation |  Martin LJ; Koegl M; Bader G; Cockcroft XL; Fedorov O; Fiegen D; Gerstberger T; Hofmann MH; Hohmann AF; Kessler D; Knapp S; Knesl P; Kornigg S; Müller S; Nar H; Rogers C; Rumpel K; Schaaf O; Steurer S; Tallant C; Vakoc CR; Zeeb M; Zoephel A; Pearson M; Boehmelt G; McConnell D Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem 59:4462-75 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 2 |
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| Name: | Bromodomain-containing protein 2 |
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| Synonyms: | Bromodomain-containing protein 2 | Bromodomain-containing protein 2 (BRD2) |
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| Type: | Protein |
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| Mol. Mass.: | 88085.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25440 |
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| Residue: | 801 |
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| Sequence: | MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPAN
PPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQP
MDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASM
PQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNI
PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA
SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKEL
LSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRL
MFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSES
SSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQG
PISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAAL
GPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGE
KLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKP
VGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSS
SDSSSSSSSSSSSDTSDSDSG
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| BDBM50183448 |
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| n/a |
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| Name | BDBM50183448 |
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| Synonyms: | CHEMBL3823478 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O3 |
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| Mol. Mass. | 353.4149 |
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| SMILES | COc1cc(cc(OC)c1CN(C)C)-c1cn(C)c(=O)c2cnccc12 |
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| Structure | 
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