| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 |
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| Ligand | BDBM50183566 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586798 (CHEMBL3826483) |
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| IC50 | 9338±n/a nM |
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| Citation |  Martin, LJ; Koegl, M; Bader, G; Cockcroft, XL; Fedorov, O; Fiegen, D; Gerstberger, T; Hofmann, MH; Hohmann, AF; Kessler, D; Knapp, S; Knesl, P; Kornigg, S; Müller, S; Nar, H; Rogers, C; Rumpel, K; Schaaf, O; Steurer, S; Tallant, C; Vakoc, CR; Zeeb, M; Zoephel, A; Pearson, M; Boehmelt, G; McConnell, D Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem59:4462-75 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 |
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| Name: | Bromodomain-containing protein 9 |
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| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66994.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108000 |
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| Residue: | 597 |
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| Sequence: | MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
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| BDBM50183566 |
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| n/a |
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| Name | BDBM50183566 |
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| Synonyms: | CHEMBL3822498 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2O2 |
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| Mol. Mass. | 242.2732 |
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| SMILES | Cc1cc(cn(C)c1=O)-c1ccc(cc1)C(N)=O |
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| Structure | 
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