| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 7 |
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| Ligand | BDBM50157607 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586801 (CHEMBL3826486) |
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| Kd | 909±n/a nM |
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| Citation |  Martin, LJ; Koegl, M; Bader, G; Cockcroft, XL; Fedorov, O; Fiegen, D; Gerstberger, T; Hofmann, MH; Hohmann, AF; Kessler, D; Knapp, S; Knesl, P; Kornigg, S; Müller, S; Nar, H; Rogers, C; Rumpel, K; Schaaf, O; Steurer, S; Tallant, C; Vakoc, CR; Zeeb, M; Zoephel, A; Pearson, M; Boehmelt, G; McConnell, D Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem59:4462-75 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 7 |
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| Name: | Bromodomain-containing protein 7 |
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| Synonyms: | 75 kDa bromodomain protein | BP75 | BRD7 | BRD7_HUMAN | CELTIX1 | Protein CELTIX-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74135.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107970 |
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| Residue: | 651 |
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| Sequence: | MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD
RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP
LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST
MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL
KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD
MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI
VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN
ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME
MSLPEDEGHTRTLDTAKEMEITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEAE
IFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQV
TPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS
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| BDBM50157607 |
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| n/a |
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| Name | BDBM50157607 |
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| Synonyms: | CHEMBL3753082 | US11773085, Compound B24 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30ClN3O4S |
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| Mol. Mass. | 516.052 |
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| SMILES | CC(C)CS(=O)(=O)N[C@H]1CCC(=O)N([C@@H]1c1ccc(Cl)cc1)c1ccc2c(C)cc(=O)n(C)c2c1 |r| |
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| Structure | 
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