| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50187591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1590501 (CHEMBL3830977) |
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| Ki | 80±n/a nM |
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| Citation |  Szymanska, E; Drabczynska, A; Karcz, T; Müller, CE; Köse, M; Karolak-Wojciechowska, J; Fruzinski, A; Schabikowski, J; Doroz-Plonka, A; Handzlik, J; Kiec-Kononowicz, K Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors. Bioorg Med Chem24:4347-4362 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50187591 |
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| n/a |
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| Name | BDBM50187591 |
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| Synonyms: | CHEMBL3827331 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H46N6O3 |
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| Mol. Mass. | 538.7246 |
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| SMILES | CCCCn1c2nc3N(CCc4ccc(OCCN(CC)CC)cc4)CCCn3c2c(=O)n(CCCC)c1=O |
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| Structure | 
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