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TargetPlatelet-activating factor acetylhydrolase IB subunit beta
LigandBDBM50132713
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1589931
IC50 72±n/a nM
Citation Sarma BKLiu XKodadek T Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorg Med Chem 24:3953-3963 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor acetylhydrolase IB subunit beta
Name:Platelet-activating factor acetylhydrolase IB subunit beta
Synonyms:PAF acetylhydrolase 30 kDa subunit | PAF-AH 30 kDa subunit | PAF-AH subunit beta | PAFAH subunit beta | PAFAH1B2 | PAFAHB | Platelet-activating factor acetylhydrolase IB subunit beta
Type:PROTEIN
Mol. Mass.:25565.45
Organism:Homo sapiens (Human)
Description:ChEMBL_18054
Residue:229
Sequence:
MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
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  Blast E-value cutoff:
BDBM50132713
n/a
NameBDBM50132713
Synonyms:Arachidonic acid derivative | CHEMBL113262 | Methyl arachidonoyl fluorophophonate | methyl ((5Z,8Z,11Z,14Z)-2-Icosa-5,8,11,14-tetraenyl)phosphonofluoridoate | methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenylphosphonofluoridate | methyl -icosa-5,8,11,14-tetraenylphosphonofluoridate | methyl(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenylphosphonofluoridate | methylarachidonyl fluorophosphonate
TypeSmall organic molecule
Emp. Form.C21H36FO2P
Mol. Mass.370.4815
SMILESCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC
Structure
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