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TargetPlatelet-activating factor acetylhydrolase IB subunit alpha2
LigandBDBM50188236
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1589931 (CHEMBL3830921)
IC50 161000±n/a nM
Citation Sarma, BKLiu, XKodadek, T Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorg Med Chem24:3953-3963 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor acetylhydrolase IB subunit alpha2
Name:Platelet-activating factor acetylhydrolase IB subunit alpha2
Synonyms:PA1B2_HUMAN | PAF acetylhydrolase 30 kDa subunit | PAF-AH 30 kDa subunit | PAF-AH subunit beta | PAFAH subunit beta | PAFAH1B2 | PAFAHB | Platelet-activating factor acetylhydrolase IB subunit beta
Type:PROTEIN
Mol. Mass.:25565.45
Organism:Homo sapiens (Human)
Description:ChEMBL_18054
Residue:229
Sequence:
MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
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  Blast E-value cutoff:
BDBM50188236
n/a
NameBDBM50188236
Synonyms:CHEMBL3827742
TypeSmall organic molecule
Emp. Form.C68H83BrClN17O18S
Mol. Mass.1573.912
SMILESCOCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1
Structure
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