| Reaction Details |
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 | Report a problem with these data |
| Target | Chromobox protein homolog 7 |
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| Ligand | BDBM50189696 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1590117 (CHEMBL3829385) |
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| Ki | 4800±n/a nM |
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| Citation |  Ren, C; Smith, SG; Yap, K; Li, S; Li, J; Mezei, M; Rodriguez, Y; Vincek, A; Aguilo, F; Walsh, MJ; Zhou, MM Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7. ACS Med Chem Lett7:601-5 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chromobox protein homolog 7 |
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| Name: | Chromobox protein homolog 7 |
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| Synonyms: | CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7) |
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| Type: | Protein |
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| Mol. Mass.: | 28351.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 251 |
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| Sequence: | MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEK
EERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKA
GAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAP
DVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAA
EGFFRDRSGKF
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| BDBM50189696 |
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| n/a |
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| Name | BDBM50189696 |
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| Synonyms: | CHEMBL3827924 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N4O6 |
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| Mol. Mass. | 470.5182 |
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| SMILES | COc1cccc(C(=O)N2CCN(CC2)C(=O)COc2cc(C)c(NC(N)=O)c(C)c2)c1OC |
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| Structure | 
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