| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydropteroate synthase |
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| Ligand | BDBM50190582 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1589225 (CHEMBL3830118) |
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| IC50 | 1900±n/a nM |
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| Citation |  Zhao, Y; Shadrick, WR; Wallace, MJ; Wu, Y; Griffith, EC; Qi, J; Yun, MK; White, SW; Lee, RE Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. Bioorg Med Chem Lett26:3950-4 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydropteroate synthase |
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| Name: | Dihydropteroate synthase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30967.84 |
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| Organism: | Bacillus anthracis |
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| Description: | ChEMBL_595739 |
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| Residue: | 280 |
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| Sequence: | MCSLKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGA
HIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAH
IINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVR
DENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEG
TGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKGVK
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| BDBM50190582 |
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| n/a |
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| Name | BDBM50190582 |
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| Synonyms: | CHEMBL3827911 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N9O5S |
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| Mol. Mass. | 485.476 |
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| SMILES | COc1cc(NS(=O)(=O)c2ccc(NCc3cnc4nc(N)[nH]c(=O)c4n3)cc2)nc(OC)n1 |
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| Structure | 
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