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TargetLarge neutral amino acids transporter small subunit 3
LigandBDBM50190653
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1612369 (CHEMBL3854169)
IC50 15500±n/a nM
Citation Wibowo, M; Levrier, C; Sadowski, MC; Nelson, CC; Wang, Q; Holst, J; Healy, PC; Hofmann, A; Davis, RA Bioactive Dihydro-ß-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis. J Nat Prod79:1445-53 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Large neutral amino acids transporter small subunit 3
Name:Large neutral amino acids transporter small subunit 3
Synonyms:L-type amino acid transporter 3 | LAT3 | LAT3_HUMAN | Large neutral amino acids transporter small subunit 3 | PB39 | POV1 | Prostate cancer overexpressed gene 1 protein | SLC43A1 | Solute carrier family 43 member 1 | Synonyms=LAT3
Type:PROTEIN
Mol. Mass.:61481.76
Organism:Homo sapiens (Human)
Description:ChEMBL_100162
Residue:559
Sequence:
MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQ
DEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTL
MALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAI
TFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLA
LDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLC
SPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFG
AMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAI
SAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLT
GLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQE
YAANGMGPLKVLSGSEVTA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50190653
n/a
NameBDBM50190653
Synonyms:CHEMBL3959689
TypeSmall organic molecule
Emp. Form.C28H36O9
Mol. Mass.516.58
SMILES[H][C@@]12[C@@H](OC(C)=O)[C@]3(OC1(C)C)[C@H](C)CC[C@H](OC(C)=O)[C@@]3(C)[C@H](OC(=O)c1ccccc1)[C@@H]2OC(C)=O |r|
Structure
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