| Reaction Details |
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 | Report a problem with these data |
| Target | Leukocyte surface antigen CD47 |
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| Ligand | BDBM50192015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1613291 (CHEMBL3855091) |
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| Kd | 6200±n/a nM |
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| Citation |  Denèfle, T; Boullet, H; Herbi, L; Newton, C; Martinez-Torres, AC; Guez, A; Pramil, E; Quiney, C; Pourcelot, M; Levasseur, MD; Lardé, E; Moumné, R; Ogi, FX; Grondin, P; Merle-Beral, H; Lequin, O; Susin, SA; Karoyan, P Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure-Activity Relationship Studies. J Med Chem59:8412-21 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukocyte surface antigen CD47 |
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| Name: | Leukocyte surface antigen CD47 |
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| Synonyms: | Antigenic surface determinant protein OA3 | CD47 | CD47_HUMAN | CD_antigen=CD47 | IAP | Integrin-associated protein | Leukocyte surface antigen CD47 | MER6 | Protein MER6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35214.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116544 |
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| Residue: | 323 |
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| Sequence: | MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKF
KGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELT
REGETIIELKYRVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGGMDEKTIALL
VAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHYYVFSTAIGLTSFVIA
ILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLGLVYMKFVASNQKTIQ
PPRKAVEEPLNAFKESKGMMNDE
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| BDBM50192015 |
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| n/a |
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| Name | BDBM50192015 |
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| Synonyms: | CHEMBL3900522 |
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| Type | Small organic molecule |
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| Emp. Form. | C65H98N14O12S |
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| Mol. Mass. | 1299.625 |
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| SMILES | CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](N)CCCCN)C(C)C)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCCCN)C(O)=O |r| |
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| Structure | 
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