| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aurora kinase B |
|---|
| Ligand | BDBM50193017 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1614097 |
|---|
| IC50 | 4.6±n/a nM |
|---|
| Citation |  Ferguson, FM; Ni, J; Zhang, T; Tesar, B; Sim, T; Kim, ND; Deng, X; Brown, JR; Zhao, JJ; Gray, NS Discovery of a Series of 5,11-Dihydro-6 ACS Med Chem Lett7:908-912 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aurora kinase B |
|---|
| Name: | Aurora kinase B |
|---|
| Synonyms: | AIK2 | AIM-1 | AIM1 | AIRK2 | ARK2 | AURKB | AURKB_HUMAN | Aurora B kinase (aurB) | Aurora B-INCENP | Aurora kinase 2 | Aurora kinase B (AURKB) | Aurora-related kinase 2 | STK-1 | STK1 | STK12 | STK5 | Serine/threonine-protein kinase aurora B |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 39327.72 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96GD4 |
|---|
| Residue: | 344 |
|---|
| Sequence: | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
|
|
|
|---|
| BDBM50193017 |
|---|
| n/a |
|---|
| Name | BDBM50193017 |
|---|
| Synonyms: | CHEMBL3904942 | US11155556, No. 17 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18N6O3S |
|---|
| Mol. Mass. | 410.45 |
|---|
| SMILES | CN1c2ccccc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(N)(=O)=O)nc12 |
|---|
| Structure | 
|
|---|
Search and Browse
