| Reaction Details |
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 | Report a problem with these data |
| Target | Nischarin |
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| Ligand | BDBM50138500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1614180 (CHEMBL3855980) |
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| Ki | 19±n/a nM |
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| Citation |  Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W Combined Interactions with I ACS Med Chem Lett7:956-961 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nischarin |
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| Name: | Nischarin |
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| Synonyms: | Imidazoline I1 | NISCH_RAT | Nisch | Nischarin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 166460.59 |
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| Organism: | RAT |
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| Description: | Q4G017 |
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| Residue: | 1502 |
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| Sequence: | MAAATLSFGPEREAEPAKEARVVGSELVDTYTVYVIQVTDGNHEWTIKHRYSDFHDLHEK
LVAERKIDKTLLPPKKIIGKNSRSLVEKREKDLEVYLQTLLKTFPDVAPRVLAHFLHFHL
YEINGVTAALAEELFEKGEQLLGAGEVFAIRPLQLYAITEQLQQGKPTCASGDAKTDLGH
ILDFTCRLKYLKVSGTEGPFGTSNIREQLLPFDLSIFKSLHQVEMSHCDAKHVRGLVTSK
PTLATMSVRFSAASMKEVLVPEASEFDEWEPEGTTLGGPVTAVIPTWQALTTLDLSHNSI
SEIDESVKLIPKIEYLDLSHNGVLVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKT
LNLAGNFLERLSGLHKLYSLVNLDLRDNRIEQLDEVKSIGNLPCLEHVALLNNPLSIIPD
YRTKVLSQFGERASEICLDDVATTEKELDTVEVLKAIQKAKDVKSKLSSTEKKVGEDFRL
PTAPCIRPSSSPPTAVPTSASLPQPILSNQGIMFVQEEALASSLSSTDSLPPDDRPIAQA
CSNSMGSLPTGQVAAEDLRDLPGAVGGVSPDHAEPEVQVVPGSGQIIFLPFTCIGYTATN
QDFIQRLSTLIRQAIERQLPAWIEAANQREEAHGEQGEEEEEEEEEDVAESRYFEMGPPD
AEEEEGSGQGEEDEEDEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSI
RQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLVL
KVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFY
KVAGGSQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAVK
SAAIPYWLLLTSQHLNVIKADFNPMPSRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQP
RGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLKDLKTVVIAKNPSARPR
TQGPLAGGQPAKSRVSAEQRLQETPAEAPAPAPAAAESAAEAPAAAEASAPAGAPAPAGA
PAPAGAPAGAQAPAPAQAEVPAQYPSERLIQSTSEENQIPSHLPVCPSLQHIARLRGRAI
IDLFHSSIAEVENEELRHLLWSSVVFYQTPGLEVTACVLLSTKAVYFILHDGLRRYFSEP
LQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQYFRLTGSSPTQVVTCLTRDS
YLTHCFLQHLMLVLSSLERTPSPEPIDKDFYSEFGDKNTGKMENYELIHSSRVKFTYPSE
EEVGDLTYVVAQKMADPAKNPALSILLYIQAFQVITPQLGRGRGPLRPKTLLLTSAEIFL
LDEDYIHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYNPYPQALTLVFDDTQGHDL
MGSVTLDHFGEMPGGPGRAGQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVEL
TG
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| BDBM50138500 |
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| n/a |
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| Name | BDBM50138500 |
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| Synonyms: | 2-((E)-Styryl)-4,5-dihydro-1H-imidazole | 2-styryl-4,5-dihydro-1H-imidazole | CHEMBL275970 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2 |
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| Mol. Mass. | 172.2264 |
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| SMILES | C1CN=C(N1)\C=C\c1ccccc1 |c:2| |
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| Structure | 
|
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