| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50000214 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1614152 (CHEMBL3855952) |
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| EC50 | 63±n/a nM |
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| Citation |  Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W Combined Interactions with I ACS Med Chem Lett7:956-961 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 48979.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08913 |
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| Residue: | 450 |
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| Sequence: | MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG
PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA
APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD
HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50000214 |
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| n/a |
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| Name | BDBM50000214 |
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| Synonyms: | CHEMBL337862 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N3 |
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| Mol. Mass. | 251.3263 |
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| SMILES | C(Nc1ccccc1-c1ccccc1)C1=NCCN1 |t:16| |
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| Structure | 
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