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TargetChromobox protein homolog 8
LigandBDBM50194449
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1616629
IC50 700±n/a nM
Citation Stuckey JISimpson CNorris-Drouin JLCholensky SHLee JPasca RCheng NDickson BMPearce KHFrye SVJames LI Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains. J Med Chem 59:8913-8923 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chromobox protein homolog 8
Name:Chromobox protein homolog 8
Synonyms:CBX8 | PC3 | Pc3 | Polycomb 3 homolog | RC1 | Rectachrome 1 | hPc3
Type:PROTEIN
Mol. Mass.:43415.86
Organism:Homo sapiens (Human)
Description:ChEMBL_108272
Residue:389
Sequence:
MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER
EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA
REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER
GTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGK
FPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGAL
DPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK
VVVTDVTSNFLTVTIKESNTDQGFFKEKR
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BDBM50194449
n/a
NameBDBM50194449
Synonyms:CHEMBL3905193
TypeSmall organic molecule
Emp. Form.C45H70N6O8
Mol. Mass.823.0727
SMILESCCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Structure
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