| Reaction Details |
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 | Report a problem with these data |
| Target | Chromobox protein homolog 8 |
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| Ligand | BDBM50194431 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1616629 |
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| IC50 | >60000±n/a nM |
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| Citation |  Stuckey JI; Simpson C; Norris-Drouin JL; Cholensky SH; Lee J; Pasca R; Cheng N; Dickson BM; Pearce KH; Frye SV; James LI Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains. J Med Chem 59:8913-8923 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chromobox protein homolog 8 |
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| Name: | Chromobox protein homolog 8 |
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| Synonyms: | CBX8 | PC3 | Pc3 | Polycomb 3 homolog | RC1 | Rectachrome 1 | hPc3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43415.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108272 |
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| Residue: | 389 |
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| Sequence: | MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEER
EREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA
REGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERER
GTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGK
FPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGAL
DPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEK
VVVTDVTSNFLTVTIKESNTDQGFFKEKR
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| BDBM50194431 |
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| n/a |
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| Name | BDBM50194431 |
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| Synonyms: | CHEMBL3954152 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H57N7O9 |
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| Mol. Mass. | 767.9114 |
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| SMILES | COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r| |
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| Structure | 
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