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TargetChromobox protein homolog 5
LigandBDBM50194474
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1616626
IC50 14000±n/a nM
Citation Stuckey JISimpson CNorris-Drouin JLCholensky SHLee JPasca RCheng NDickson BMPearce KHFrye SVJames LI Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains. J Med Chem 59:8913-8923 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chromobox protein homolog 5
Name:Chromobox protein homolog 5
Synonyms:Antigen p25 | CBX5 | Chromobox protein homolog 5 | HP1 alpha | HP1A | Heterochromatin protein 1 homolog alpha
Type:PROTEIN
Mol. Mass.:22222.71
Organism:Homo sapiens (Human)
Description:ChEMBL_116826
Residue:191
Sequence:
MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCP
ELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERG
LEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPED
AENKEKETAKS
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BDBM50194474
n/a
NameBDBM50194474
Synonyms:CHEMBL3953637
TypeSmall organic molecule
Emp. Form.C41H62N6O8
Mol. Mass.766.9664
SMILESCCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(CC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Structure
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