| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5'-AMP-activated protein kinase subunit beta-1 |
|---|
| Ligand | BDBM50195477 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1617782 (CHEMBL3859851) |
|---|
| EC50 | 0.700000±n/a nM |
|---|
| Citation |  Cameron, KO; Kurumbail, RG Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators. Bioorg Med Chem Lett26:5139-5148 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5'-AMP-activated protein kinase subunit beta-1 |
|---|
| Name: | 5'-AMP-activated protein kinase subunit beta-1 |
|---|
| Synonyms: | 5'-AMP-activated protein kinase subunit beta-1 | AAKB1_HUMAN | AMP-activated protein kinase alpha-2/beta-1/gamma-3 | AMPK | AMPK subunit beta-1 | AMPKb | PRKAB1 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 30380.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9Y478 |
|---|
| Residue: | 270 |
|---|
| Sequence: | MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
|
|
|
|---|
| BDBM50195477 |
|---|
| n/a |
|---|
| Name | BDBM50195477 |
|---|
| Synonyms: | CHEMBL3979403 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H16ClN3O4 |
|---|
| Mol. Mass. | 421.833 |
|---|
| SMILES | COc1cc(on1)C(O)=C1C(=O)Nc2cc(Cl)c(cc12)-c1ccc2n(C)ccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
