| Reaction Details |
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 | Report a problem with these data |
| Target | Heat sensitive channel TRPV3 |
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| Ligand | BDBM50197971 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1620335 (CHEMBL3862618) |
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| IC50 | 21700±n/a nM |
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| Citation |  Pollastro, F; Golin, S; Chianese, G; Putra, MY; Schiano Moriello, A; De Petrocellis, L; García, V; Munoz, E; Taglialatela-Scafati, O; Appendino, G Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study. J Nat Prod79:1762-8 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heat sensitive channel TRPV3 |
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| Name: | Heat sensitive channel TRPV3 |
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| Synonyms: | Heat sensitive channel TRPV3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 90273.53 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_116972 |
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| Residue: | 791 |
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| Sequence: | MKAHPKEMVPLMGKRTTAPGGNPAVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTS
PPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLK
KCIFAAVSEGCVRELRELLQDLQELCRRRRGLDASDFLMHKLTASDTGKTCLMKALLNIN
PNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGAD
VNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNIL
HALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYI
LGREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEVL
TLEPLHTLLHMKWKKFAKYMFFLSFCFYFSYNITLTLVSYYRPREGEALPHPLALTHKMS
WLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVIFGQAVLVILSVFLY
LFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLG
FGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGGLNIQQNSTYPILFLFLLIT
YVILTFVLLLNMLIALMGETAENVSKESERIWRLQRARTTLEFEKMLPEWLRSRFRMGEL
CKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADSNKIQDSSRSNSKTTLYAF
DELDEFPETSV
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| BDBM50197971 |
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| n/a |
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| Name | BDBM50197971 |
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| Synonyms: | CHEMBL3890789 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40O3 |
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| Mol. Mass. | 424.6154 |
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| SMILES | CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(=O)Cc1ccccc1 |r,t:14,19| |
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| Structure | 
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