| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50203126 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1623458 (CHEMBL3865870) |
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| IC50 | 10000±n/a nM |
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| Citation |  Haranahalli, K; Tong, S; Ojima, I Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ. Bioorg Med Chem24:6354-6369 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_ECOLI | ftsZ | sfiB | sulB |
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| Type: | Protein |
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| Mol. Mass.: | 40305.83 |
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| Organism: | Escherichia coli |
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| Description: | P0A9A6 |
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| Residue: | 383 |
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| Sequence: | MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQI
GSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVA
KDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLD
AFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAA
EMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDP
DMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVND
NAPQTAKEPDYLDIPAFLRKQAD
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| BDBM50203126 |
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| n/a |
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| Name | BDBM50203126 |
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| Synonyms: | 3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrido[2,1-a]isoquinolin-5-ylium | 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium | 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride | 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium; chloride | BERBERINE | Berberinechloride | CHEMBL12089 | berberine dimer | cid_12456 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18NO4 |
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| Mol. Mass. | 336.3607 |
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| SMILES | COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC |
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| Structure | 
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