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TargetC-C chemokine receptor type 3
LigandBDBM50202470
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1624212
EC50 1400±n/a nM
Citation Morikawa THachiman IMatsuo KNishida ENinomiya KHayakawa TYoshie OMuraoka ONakayama T Neolignans from the Arils of Myristica fragrans as Potent Antagonists of CC Chemokine Receptor 3. J Nat Prod 79:2005-13 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 3
Name:C-C chemokine receptor type 3
Synonyms:C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CD_antigen=CD193 | CKR3 | Eosinophil eotaxin receptor
Type:Enzyme
Mol. Mass.:41053.88
Organism:Homo sapiens (Human)
Description:P51677
Residue:355
Sequence:
MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50202470
n/a
NameBDBM50202470
Synonyms:CHEMBL3922119
TypeSmall organic molecule
Emp. Form.C24H30O7
Mol. Mass.430.4908
SMILESCOc1ccc(cc1OC)[C@@H](OC(C)=O)[C@H](C)Oc1c(OC)cc(CC=C)cc1OC |r|
Structure
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