| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50202521 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1624519 (CHEMBL3866931) |
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| Ki | 1197±n/a nM |
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| Citation |  Osman, NA; Ligresti, A; Klein, CD; Allarà, M; Rabbito, A; Di Marzo, V; Abouzid, KA; Abadi, AH Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality. Eur J Med Chem122:619-634 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50202521 |
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| n/a |
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| Name | BDBM50202521 |
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| Synonyms: | CHEMBL3962080 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N2O |
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| Mol. Mass. | 362.5078 |
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| SMILES | CCc1c(cc(C)n1-c1ccccc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:20:21:18.19.24:25,THB:20:19:25:26.21.22,22:21:18:24.23.25,22:23:18:26.20.21| |
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| Structure | 
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